Analysis of the Alu insertion polymorphism in urban and rural Russian populations of Siberia

作者：Stepanov VA^*; Puzyrev VP; Spiridonova MG; Khitrinskaya IY

来源：Russian Journal of Genetics, 1999, 35(8): 979-983.

Polymorphic Alu-repeat loci of human genome are commonly used as effective genetic markers in population and evolution studies. In this work, the data on genetic structure of two Russian populations from Siberia obtained via analysis of five polymorphic Alu repeats are presented. The urban population was characterized by a slightly higher level of genetic diversity compared to the rural population. The value of genetic differentiation coefficient for the populations studied was 0.57%, pointing to the absence of genetic subdivision within the urban and rural populations. Phylogenetic analysis of these populations, together with literature data, shows that, with respect to the markers examined, the gene pool structure of the Russian population is similar to that of other Caucasoid populations.

• 出版日期1999-8
• 单位河北医科大学