Differences in autonomic neural activity during exercise between the second and third trimesters of pregnancy

作者：Nakagaki Akemi^*; Inami Takayuki; Minoura Tetsuji; Baba Reizo; Iwase Satoshi; Sato Motohiko

来源：Journal of Obstetrics and Gynaecology Research, 2016, 42(8): 951-959.

DOI：10.1111/jog.12990

• autonomic neural activity
• exercise
• pregnant women
• second trimester
• third trimester

AimTo test the hypothesis that autonomic neural activity in pregnant women during exercise varies according to gestational age.
MethodsThis cross-sectional study involved 20 healthy women in their second (n = 13) or third (n = 7) trimester of pregnancy. Incremental cardiopulmonary exercise testing was performed with an electromagnetic cycle ergometer. Heart rate variability was analyzed by frequency analysis software.
ResultsThe low-frequency to high-frequency (LF/HF) ratio, an indicator of the sympathetic nervous system, was significantly higher in third trimester than in second trimester subjects (P < 0.05) at 1, 2, and 3 min of incremental exercise testing. In contrast, the HF/total power ratio, an indicator of rapidly acting parasympathetic activity, was significantly higher in second trimester than in third trimester subjects (P < 0.05) at 2 and 3 min. In addition, a negative correlation was found between gestational age and the accumulation half-time' of the LH/HF ratio, the time point at which the sum of the LF/HF ratio reached 50% of that accumulated in the total 6 min of exercise testing (r = -0.49, P = 0.028).
ConclusionsThe autonomic response to exercise in pregnant women differs between the second and third trimesters. These differences should be considered when prescribing exercise to pregnant women.

• 出版日期2016-8