Acute Exacerbation of Idiopathic Pulmonary Fibrosis An International Working Group Report

作者：Collard Harold R; Ryerson Christopher J; Corte Tamera J; Jenkins Gisli; Kondoh Yasuhiro; Lederer David J; Lee Joyce S; Maher Toby M; Wells Athol U; Antoniou Katerina M; Behr Juergen; Brown Kevin K; Cottin Vincent; Flaherty Kevin R; Fukuoka Junya; Hansell David M; Johkoh Takeshi; Kaminski Naftali; Kim Dong Soon; Kolb Martin; Lynch David A; Myers Jeffrey L; Raghu Ganesh; Richeldi Luca; Taniguchi Hiroyuki; Martinez Fernando J

来源：American Journal of Respiratory and Critical Care Medicine, 2016, 194(3): 265-275.

DOI：10.1164/rccm.201604-0801CI

• pulmonary fibrosis
• acute exacerbation
• review
• diagnosis
• management

Acute exacerbation of idiopathic pulmonary fibrosis has been defined as an acute, clinically significant, respiratory deterioration of unidentifiable cause. The objective of this international working group report on acute exacerbation of idiopathic pulmonary fibrosis was to provide a comprehensive update on the topic. A literature review was conducted to identify all relevant English text publications and abstracts. Evidence-based updates on the epidemiology, etiology, risk factors, prognosis, and management of acute exacerbations of idiopathic pulmonary fibrosis are provided. Finally, to better reflect the current state of knowledge and improve the feasibility of future research into its etiology and treatment, the working group proposes a new conceptual framework for acute respiratory deterioration in idiopathic pulmonary fibrosis and a revised definition and diagnostic criteria for acute exacerbation of idiopathic pulmonary fibrosis.

• 出版日期2016-8-1