Anti-inflammatory Drugs Interacting with Cu(II) Metal Ion Synthesis, characterization and thermal behaviour of the complex with ketoprofen

作者：Tita Bogdan; Furau Gheorghe^*; Marian Eleonora; Tita Dumitru; Furau Cristian

来源：Revista de Chimie, 2016, 67(4): 706-710.

• anti-inflammatory drug
• ketoprofen
• FT-IR spectroscopy
• X-ray analysis
• thermal analysis

New metal (II) complex with empirical formula [Cu(KET)(2)](2)center dot 0.5H(2)O (where KET = C6H5COC6H4CH(CH3)COO-) was isolated and investigated. The elemental analysis, Fourier transformed infrared spectroscopy FT-IR), X-ray diffraction powder (XRPD) and thermal analysis were used to study solid Ketoprofen (KET) of Cu(II) metal ion. The thermal behavior was studied by thermogravimetry (TG), derivative thermogravimetry (DTG) and differential scaning calorimetry (DSC) methods under non-isothermal conditions in a dynamic air atmosphere. The results provided informations of the composition, structure, thermal behavior and thermal decomposition. The FT-IR spectra of studied complex revealed also absorption of the carboxylate group, for which is important the position of asymmetric, symmetric frequencies. The value of their separation allow to deduce about type of coordination these groups.

• 出版日期2016-4