BALLOON-EXPANDABLE STENTS EXPANSION IN TAPERED VESSELS AND THEIR INTERACTIONS

作者:Shen, Xiang*; Xie, Zhong-Min; Sun, Yang-Yang; Wu, Bo-Bo
来源:Journal of Mechanics in Medicine and Biology, 2014, 14(6): 1440013.
DOI:10.1142/S0219519414400132

摘要

In-stent restenosis (ISR) after stent implantation, especially in tapered vessels, remains an obstacle in the long-term benefits of stenting. In the present study, a finite element method (FEM) was employed to investigate the expansion process of balloon-expandable stents in tapered vessels (the TV model) and their interactions. For comparison, a numerical model of the same stent deployment in a straight vessel was also investigated. Results showed that in the TV model, the peak tissue stresses took place at the distal end of the tapered vessel. The node displacements of the stent's proximal and distal ends remained consistent before the stent contacted the tapered vessel, while the proximal end was larger than the distal end after the stent contacted the tapered vessel. The regions of maximum stresses in the stent after expansion were concentrated in the corners of the diamond cells of the stent's proximal end. The investigation provided some interpretations of the clinical observations in tapered vessels and also provided stent design proposals for tapered vessels. The FEM quantified the mechanical properties of stents in tapered vessels, and can help clinicians select appropriate stents, assist designers in pretests and create new stents made especially for tapered vessels.