A COMPARATIVE SURVEY OF SURVIVAL OF CARDIAC PATIENTS WITH 3VD AND SEVER VENTRICULAR HEART FAILURE UNDER CABG AND MFU TREATMENTS USING COX REGRESSION

作者：Farhadi Khosro; Shetabi Hamidreza; Saman Javad Amini; Karimpour Hass****i; Eskandari Soudabeh^*; Cheghazardi Shahrokh

来源：Acta Medica Mediterranea, 2016, 32: 2038-2042.

• survival analysis
• cardiac patients
• CABG
• MFUtion
• emotion regulation difficulties

Introduction: Cardiac diseases are of the most prevalent causes of death in the developed countries and the whole world as well. According to the forecasts by the World Health Organization, the diseases will be the main cause of death in the world by 2020. The most common surgery operation in coronary artery disease is coronary artery bypass grafting (CABG) and medical follow-up (MFU). Survival of 3VD and severe ventricular heart failure patients in two groups of CABG and MFU was compared.
Methodology: A retrospective cohort study on 269 patients between 2009 and 2011 was carried out in Imam Ali Medical Educational Center. The 3VD patients underwent coronary artery angiography and had EF <30% so that CABG was prescribed form them. Male and female constituted 78% and 22% of the study group and average age of the participants was 61.40 +/- 9.07. The patients were categorized in two groups of CABG and MFU. Follow up was carried out until November 2014 to record any case of death. Kaplan-Meier survival analysis and Cox regression were used for data analysis. All the analyses were performed in STATA (12) with sig.= 0.05.
Findings: The results showed that despite their clear effects on development of coronary artery problems, the demographic information had no significant effect on clinical outcome of the patients. One month, six months, one year, and three years survival of CABG patients was 96.7%, 95.3%, 94.7%, and 89.8% respectively and these figures for the pharmaceutical medication patients were 97%, 92.5%, 86.3%, and 83.4% respectively. In addition, survival term in MFU and CABG patients was 52.80 +/- 1.64 and 57.15 +/- 1.23 months respectively. The most important factor effective on survival of patients according to Cox regression model was left ventricular EF.
Conclusion: The findings indicated that survival rate was significantly related to the type of medical intervention. That is, survival rate of CABG group was higher than that of MFU group. Risk rate of CABG and MFU patients increased considerably after 30 and 20 months respectively.