An eco-friendly procedure for the efficient synthesis of bis(indolyl)methanes in aqueous media

作者:Sobhani Sara*; Safaei Elham; Hasaninejad Ali Reza; Rezazadeh Soodabeh
来源:Journal of Organometallic Chemistry, 2009, 694(18): 3027-3031.
DOI:10.1016/j.jorganchem.2009.05.004

摘要

A new, convenient and high yielding procedure for the preparation of bis(indolyl) methanes in water by electrophilic substitution reaction of indoles with different carbonyl compounds in the presence of a catalytic amount of [Cu(3,4-tmtppa)](MeSO(4))(4) (1 mol%) as a highly stable and reusable catalyst is described. This procedure has also been applied successfully for the preparation of bis(pyrazole-5-ols) and dipyrromethanes.

  • 出版日期2009-8-15