Microwave-assisted synthesis of N-heterocycle-based organometallics

作者：Schmidlehner Melanie; Kuhn Paul Steffen; Hackl Carmen M; Roller Alexander; Kandioller Wolfgang^*; Keppler Bernhard K

来源：Journal of Organometallic Chemistry, 2014, 772: 93-99.

DOI：10.1016/j.jorganchem.2014.08.013

• Organometallic chemistry
• Half-sandwich complexes
• Microwave chemistry
• Nitrogen heterocycles
• Organometallic building blocks

A series of 15 different metal-arene-complexes of the general formula [M(arene)(azole)2CIICI and [M(arene)(azole)Cl-2], where M = Ru (1-4), Os (5-8), Rh (9-12) or Ir (13-15), arene = eta(6)-p-cymene or 1,2,3,4,5-pentamethylcyclopentadienyl and azole = 1-Me-imidazole, 1H-pyrazole, 1H-benzimidazole or morpholine, has been synthesized under microwave conditions. The reaction time was dramatically reduced from several hours to a few minutes, accompanied by smaller solvent amounts and - in some cases - an increased yield. The organometallic complexes have been characterized by standard analytical methods, the reaction conditions have been optimized and the solid state structures of several examples are reported. The obtained organometallic complexes can be utilized as building blocks for potential metallodrugs or catalysts.

• 出版日期2014-12-1