Assessing variability in neonatal blood pressure, notably in hypotension

作者：Cornelissen Germaine^*; Halberg Franz; Syutkina Elena Vasilievna; Yatsyk Galina Victorovna; Masalov Anatoly Victorovich; Schwartzkopff Othild; Johnson Dana

来源：Journal of Applied Biomedicine, 2010, 8(4): 209-211.

DOI：10.2478/v10136-009-0029-1

• blood pressure
• chronomics
• circadian
• ischemic cerebral injury
• hypotension
• neurological development

New reports corroborate our prior finding that hypotension in infancy is associated with impaired neurodevelopment later in childhood. We had also found that neurological deficit is further associated with a more pronounced circadian variation in transcutaneous pO(2) (tcpO(2)). New evidence in adulthood prompts the recommendation to automatically monitor vital signs for continued surveillance, relying on the methods of chronobiology for data analysis as-one-goes. This applies notably early in extra-uterine life when infants may be particularly sensitive to ischemic cerebral injury secondary to systemic hypotension. Monitoring at this sensitive lifetime stage has also provided a glimpse of unseen effects of the cosmos on the patterns of blood pressure variability, detected by chronomics.

• 出版日期2010-12