科研之友
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摘要
A simple, facile and convenient strategy has been developed for the synthesis of dihydropyrimidine-5-carboxamides in low melting mixture of betaine hydrochloride/urea. In this procedure, the low melting mixture of betaine hydrochloride/urea plays a triple role: as a catalyst, solvent and reactant. The present green protocol has advantages such as high yield of products, short reaction times, operational simplicity, no chromatographic separation, eco-friendliness, and applicability for large-scale synthesis.
- 出版日期2016-6
- 单位河北师范大学
