科研之友
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摘要
Two onium ion-tagged prolines, imidazolium bis(trifluoromethylsulfonyl)imide-substituted proline 6 and butyldimethylammonium bis(trifluoromethylsulfonyl)imide-substituted proline 7, were synthesised and their catalytic activity in the direct asymmetric aldol condensation was studied in ionic liquids. For the reaction of acetone with various aldehydes, using 5% of the catalyst, the yields of the aldols varied between 50-85% while the ee values were in the 80-85% range. Other ketones were studied too, the yields obtained in those cases being in the 35-78% range while the enantioselectivities varied between 75-94%.
- 出版日期2007-8
