Antimicrobial Polyurethane Thermosets Based on Undecylenic Acid: Synthesis and Evaluation

作者:Lluch Cristina; Esteve Zarzoso Braulio; Bordons Albert; Lligadas Gerard*; Ronda Juan C; Galia Marina; Cadiz Virginia
来源:Macromolecular Bioscience, 2014, 14(8): 1170-1180.
DOI:10.1002/mabi.201400017

摘要

In the present study, plant oil-derived surface-modifiable polyurethane thermosets are presented. Polyol synthesis is carried out taking advantage of thiol-yne photopolymerization of undecylenic acid derivatives containing methyl ester or hydroxyl moieties. The prepared methyl ester-containing polyurethanes allow surface modification treatment to enhance their hydrophilicity and impart antimicrobial activity through the following two steps: i) grafting poly(propylene glycol) monoamine (Jeffamine M-600) via aminolysis and ii) Jeffamine M-600 layer complexation with iodine. The antimicrobial activity of the iodine-containing polyurethanes is demonstrated by its capacity to inhibit the growth of Staphylococcus aureus, and Candida albicans in agar media.

  • 出版日期2014-8