What are the prevalence, characteristics and significance of fetal lateral neck cysts detected in an early anatomical scan?

作者：Halevy Rivka Sukenik^*; Friedler Jordana Mashiach; Hershko Klement Anat; Biron Shental Tal; Markovitch Ofer; Tepper Ronnie

来源：Archives of Gynecology and Obstetrics, 2018, 298(1): 51-58.

DOI：10.1007/s00404-018-4747-z

• Lateral neck cyst
• Aneuploidy
• Heart malformations
• Pregnancy outcome

This study evaluated the association of fetal lateral neck cysts (FLNC) with adverse pregnancy outcomes, in relation to specific sonographic characteristics and co-existing findings.
Pregnancies in which FLNC were detected by a single examiner in early anatomical scans (14-16 weeks) were included. Data regarding the pregnancy and its outcome were retrieved from telephone-based questionnaires, patient charts and from the examiner's reports.
654 cases of FLNC were detected among 9446 early anatomical scans (6.9%). Complete data regarding 219 pregnancies were available. FLNC were significantly more prevalent in males (65.2%). The prevalence of heart malformations was 3.2% [all were non-isolated cases or with abnormal nuchal translucency (NT) and/or nuchal fold (NF)]. Amniocentesis performed in 165 pregnancies was abnormal in 1.2%. Among 206 children born from this cohort, adverse medical outcomes were reported in 5.3%. The likelihood of adverse pregnancy outcomes was significantly higher in non-isolated cases and in cases with abnormal NT or NF. Sonographic characteristics such as cyst size and bilateral findings were not linked to adverse pregnancy outcomes.
Isolated FLNC are benign findings which do not require additional work up. FLNC with additional sonographic abnormalities are associated with a significantly increased risk for adverse pregnancy outcomes.

• 出版日期2018-7