Depleting senescent cells to combat aging

作者:Geiger Hartmut*
来源:Nature Medicine, 2016, 22(1): 23-24.
DOI:10.1038/nm.4024

摘要

A new study in mice suggests that pharmacologically targeting the apoptosis proteins BCL-2 and BCL-xL can clear senescent cells from bone marrow and ameliorate stem cell function during aging, bringing us a step closer to preventing senescence-associated tissue attrition in the clinic.

  • 出版日期2016-1