A new compound from the fruit of Amorpha fruticosa and activity against acetaminophen-induced hepatotoxicity

作者：Diao Yun Peng; Li Kun; Huang Shan Shan; Liu Ke Xin; Kang Ting Guo^*

来源：Chinese Chemical Letters, 2009, 20(8): 942-944.

DOI：10.1016/j.cclet.2009.03.039

• Amorpha fruticosa
• Isoflavone
• Activity against AAP

A new isoflavone was obstained from the medicinal herb Amorpha fruticosa. It was elucidated asbenzopyran-12-one,1,4,10,11-tetrahydro-6'-[8'-(hydroxymethyl)ethenyl]-2,3-dimethoxy-8'-O-beta-D-glucopyranosyl-O-alpha-D-arabinoside by spectroscopic methods including UV, IR, 1D NMR and 2D NMR techniques. And the activity against acetaminophen-induced hepatotoxicity of this compound was also studied, and found this compound can protect liver obviously from hepatotoxicity induced by acetaminophen (AAP).

• 出版日期2009-8
• 单位辽宁中医药大学; 辽宁师范大学; 大连医科大学