Bismuth (III) coordination to cyclen and cyclam bearing four appended groups

作者：Morfin Jean Francois; Tripier Raphael; Le Baccon Michel; Handel Henri^*

来源：Polyhedron, 2009, 28(17): 3691-3698.

DOI：10.1016/j.poly.2009.08.003

• Bismuth
• Cyclen
• Cyclam
• Complexation

The synthesis of new cyclam and cyclen derivatives (respectively L(1) and L(2)), able to efficiently coordinate to Bi(III) are presented here. The two ligands bearing two different pendant arms (two-pycolyl and two (2-(2-hydroxyethoxy)ethyl)-2-aminoacetamide in trans position) were synthesized in the aim to obtain stable and water soluble complexes. The thermodynamic and kinetic of the formation of the corresponding complexes in aqueous solution were studied by means of NMR and potentiometric investigations. The fast kinetic of complexation and the high stability of the complexes are encouraging for further application with the alpha-emitting (213)Bi isotope.

• 出版日期2009-11-16