Acylation of Meldrum's acid with arylacetic acid imidazolides as a convenient method for the synthesis of 4-aryl-3-oxobutanoates

作者：Shimkin A A^*; Shirinian V Z; Mailian A K; Lonshakov D V; Gorokhov V V; Krayushkin M M

来源：Russian Chemical Bulletin, 2011, 60(1): 139-142.

DOI：10.1007/s11172-011-0019-9

• beta-keto esters
• Meldrum's acid
• imidazolides
• arylacetic acids

C-Acylation of Meldrum's acid by (het)arylacetic acids in ethanol in the presence of 1,1'-carbonyldiimidazole leads to ethyl 4-(het)aryl-3-oxobutanoates in high yields.

• 出版日期2011-1