Nanotoxicity: The Toxicity Research Progress of Metal and Metal-Containing Nanoparticles

作者：Ding, Lingling; Liu, Zhidong^*; Aggrey, Mike Okweesi; Li, Chunhua; Chen, Jing; Tong, Ling

来源：Mini Reviews in Medicinal Chemistry, 2015, 15(7): 529-542.

DOI：10.2174/138955751507150424104334

• Influencing factors
• metal and metal-containing nanoparticles
• reason and mechanism
• research methods
• toxicity expressive types
• toxicity research progress

Along with the exuberant development of nanotechnology, a large number of nanoformulations or non materials are successfully applied in the clinics, biomedicine, cosmetics and industry. Despite some unique advantages of nanoformulations, there exist potentially worrying toxic effects, particularly those related to metal and metal-containing nanoparticles (NPs). Although various researches have been conducted to assess the metallic and metal-containing nanoparticles toxic effects, only little is known about the toxicity expressive types and evaluation, reasons and mechanisms, influencing factors and research methods of metal and metal-containing nanotoxicity. Therefore, it is of importance to acquire a better understanding of metal and metal-containing nanoparticles toxicity for medical application. This review presents a summary on the metal and metal-containing nanoparticles toxicity research progress consulting relevant literature.

• 出版日期2015
• 单位天津中医药大学