A selective fluorescent turn-on NIR probe for cysteine

作者：Jiang, Xin-Dong^*; Zhang, Jian; Shao, Xiangmin; Zhao, Weili

来源：Organic and Biomolecular Chemistry, 2012, 10(10): 1966-1968.

DOI：10.1039/c2ob07046d

• RESTRICTED AZA-BODIPY
• HIGHLY FLUORESCENT
• HOMOCYSTEINE
• RECOGNITION
• THIOLS
• CYSTEINE/HOMOCYSTEINE
• QUANTIFICATION
• CHEMOSENSOR
• GLUTATHIONE
• SENSORS

A selective and sensitive turn-on fluorescent NIR probe for cysteine has been developed. Cleavage of 2,4-dinitrobenzene-sulfonyl (DNBS) with thiols switches the weakly fluorescent aza-BODIPY dye (lambda(em) = 734 nm, Phi(f) = 0.03) to a strongly fluorescent species in the NIR region (lambda(em) = 755 nm, Phi(f) = 0.14).

• 出版日期2012
• 单位河南大学; 复旦大学