Anterior Urethra Reconstruction With Lateral Lingual Mucosa Harvesting Technique

作者：Zhang, Kaile; Zhou, Shukui; Zhang, Yumeng; Xu, Yuemin; Jin, Sanbao; Sa, Yinglong; Zhang, Jiong; Xie, Hong; Lazzeri, Massimo; Barbagli, Guido; Chen, Rong; Fu, Qiang^*

来源：Urology, 2016, 90: 208-212.

DOI：10.1016/j.urology.2016.01.008

• GRAFT URETHROPLASTY
• BUCCAL MUCOSA
• EXPERIENCE

OBJECTIVE To describe a new technique for harvesting the long lingual mucosal graft (LMG) to repair the long-segment urethral strictures. @@@ METHODS We performed a retrospective observational study of patients from whom LMGs were harvested from the lateral lining of the tongue for the long-segment anterior urethral strictures repair from 2012 to 2014 at the Shanghai Sixth People's Hospital. Patients who had 12 months minimum follow-up were included. Patients with incomplete clinical records were excluded. The LMG was applied on the urethra according to the dorsal onlay technique. @@@ RESULTS The primary outcome of the study was the postoperative failure-free survival rate. The secondary outcome was the rate of early and late complications at the harvesting site. Success was defined as Qmax >12 ml/s and no postoperative procedures. One hundred and one patients were included. Median stricture length was 7.1 +/- 3.6 cm; median LMG length was 7.2 +/- 3.6 cm. The success rate was 81.2% with a median follow-up of 23 months. Complications at the donor site had occurred in 41 patients at 6-months follow-up, and persisted in 18 patients at the 12-months follow-up. A bilateral harvest and harvest length were the main factors influencing complication rate (P = .0038 for 6 months and P = .1112 for 12 months). Almost half of donor site complications subsided within 12 months (P = .0018). @@@ CONCLUSION In patients requiring long oral grafts >7 cm to repair anterior strictures, a valid option is to harvest the graft from the lateral lining of the tongue.

• 出版日期2016-4
• 单位上海交通大学