A Novel Actinic Keratosis Field Assessment Scale for Grading Actinic Keratosis Disease Severity

作者：Dreno Brigitte^*; Cerio Rino; Dirschka Thomas; Figueras Nart Ignasi; Lear John T; Peris Ketty; Ruiz de Casas Andres; Kaleci Shaniko; Pellacani Giovanni

来源：ACTA DERMATO-VENEREOLOGICA, 2017, 97(9): 1108-1113.

DOI：10.2340/00015555-2710

• actinic keratosis
• field cancerization
• grading scale

Actinic keratosis (AK) lesions are surrounded by field cancerization (areas of subclinical, non-visible sun damage). Existing AK grading tools rely on AK counts, which are not reproducible. An Actinic Keratosis Field Assessment Scale (AK-FAS) for grading the severity of AK/field was developed. Standardized photographs of patients representing the full range of AK severity were collected. Six investigators independently rated each photograph according to 3 criteria: AK area (total skin area affected by AK lesions), hyperkeratosis and sun damage. Inter-rater reproducibility was good for all 3 criteria. Validation of the AK-FAS showed good reproducibility for AK area and hyperkeratosis, even for dermatologists untrained on use of the scale. In conclusion, the AK-FAS is objective, easy to use and implement, and reproducible. It incorporates assessment of the entire field affected by AK instead of relying on lesion counts. Use of the AK-FAS may standardize AK diagnosis, making it relevant to routine clinical practice.

• 出版日期2017-10