A new benzopyrans derivative from a mangrove-derived fungus Penicillium citrinum from the South China Sea

作者：Zheng, Cai-Juan; Huang, Guo-Lei; Xu, Yan; Song, Xin-Ming; Yao, Jun; Liu, Hui; Wang, Ruo-Ping; Sun, Xue-Ping^*

来源：Natural Product Research, 2016, 30(7): 821-825.

DOI：10.1080/14786419.2015.1072712

• Penicillium citrinum
• metabolites
• benzopyran derivative
• antibacterial activity

One new benzopyran derivative (2R(*),4R(*))-3,4-dihydro-5-methoxy-2-methyl-2H-1-benzopyran-4-ol (1), together with five known compounds (2-6), were obtained from the EtOAc extract of the endophytic fungus Penicillium citrinum HL-5126 isolated from the mangrove Brguiera sexangula var. rhynchopetala collected in the South China Sea. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. All compounds were evaluated for their antibacterial activities. Compound 6 exhibited potent inhibitory activity against Bacillus subtilis, Bacillus cereus and Micrococcus tetragenus with the same MIC values of 6.94M.

• 出版日期2016-4-2
• 单位广西壮族自治区海洋研究所; 海南师范大学; 广西壮族自治区海洋研究院