Accelerated Sonochemical Synthesis of Calcium Deficient Hydroxyapatite Nanoparticles: Structural and Morphological Evolution

作者：Varadarajan Namitha; Balu Rajkamal; Rana Deepti; Ramalingam Murugan; Kumar T S Sampath^*

来源：Journal of Biomaterials and Tissue Engineering, 2014, 4(4): 295-299.

DOI：10.1166/jbt.2014.1173

• Calcium Deficient Hydroxyapatite
• Sonochemical
• Nanoparticles
• Structure
• Morphology

Calcium deficient hydroxyapatite (CDHA) nanoparticles with a Ca/P ratio of 1.6 were synthesized by accelerated sonochemical process. The synthesis was carried out using calcium nitrate and diammonium hydrogen phosphate in an ultrasonic bath operated at a fixed frequency of 135 kHz and 250 Watts power. The effect of ultrasonic radiation as a function of time over the formation and structure of nanoparticles were investigated using X-ray diffraction, spectroscopy and microscopy methods. The synthesized nanocrystals showed X-ray powder diffraction pattern corresponding to that of hydroxyapatite stoichiometry with CDHA characteristics. HPO42- Fourier transform infrared vibration band observed at 875 cm(-1). Transmission electron microscopic analysis confirmed the nanocrystalline nature and growth of acicular, rod and needle-like CDHA nanocrystals morphology with increasing irradiation time.

• 出版日期2014-4