Association of polymorphisms in HTR2A, HTR1A and TPH2 genes with suicide attempts in alcohol dependence: A preliminary report

作者：Wrzosek Malgorzata; Lukaszkiewicz Jacek; Wrzosek Michal; Serafin Piotr; Jakubczyk Andrzej; Klimkiewicz Anna; Matsumoto Halina; Brower Kirk J; Wojnar Marcin^*

来源：Psychiatry Research, 2011, 190(1): 149-151.

DOI：10.1016/j.psychres.2011.04.027

• Alcoholism
• Suicide
• HTR2A

We investigated a relationship between selected polymorphisms: rs6313 in HTR2A, rs6295 in HTR1A and rs1386494 in 7PH2, and suicidal behaviour in 150 alcohol-dependent patients. There was a significant association between more frequent C102C genotype in HTR2A and suicide attempts in alcoholic females. No differences in genotype distribution in HTR1A and TPH2 SNPs were found between patients with and without suicide attempts.

• 出版日期2011-11-30