Anxiolytic effects of Salvia reuterana Boiss. on the elevated plus-maze model of anxiety in mice

作者：Rabbani M^*; Sajjadi SE; Jafarian A; Vaseghi G

来源：Journal of Ethnopharmacology, 2005, 101(1-3): 100-103.

DOI：10.1016/j.jep.2005.03.034

• anxiety
• elevated plus-maze
• Salvia reuterana Boiss.

The anxiolytic and sedative effects of hydroalcoholic extract (HE) of Salvia reuterana Boiss. was evaluated in mice. The HE of Salvia reuterana (100 mg/kg), increased the percentage of time-spent and the percentage of arm entries in the open arms of the elevated plus-maze. Spontaneous locomotor activity count measured in 15 min of the test was significantly decreased in animals pretreated with diazepam and 100 mg/kg of Salvia reuterana extract. Results of the present study provide support for the traditional usage of Salvia reuterana as a sedative and anxiolytic medicinal plant.

• 出版日期2005-10-3