Adult Multipotent Stromal Cell Technology for Bone Regeneration: A Review

作者:Lopez Mandi J*; Daigle Patrick R
来源:Veterinary Surgery, 2013, 42(1): 1-11.
DOI:10.1111/j.1532-950X.2012.01077.x

摘要

Since the discovery of bone marrow derived stromal cell osteogenesis in the 1960s, tissue engineering with adult multipotent stromal cells (MSCs) has evolved as a promising approach to restore structure and function of bone compromised by injury or disease. To date, accelerated bone formation with MSCs has been demonstrated with a variety of tissue engineering strategies. Though MSC bone tissue engineering has advanced over the last few decades, limitations to clinical translation remain. A current review of this promising field is presented with a specific focus on equine investigations.

  • 出版日期2013-1