Acetal-initiated Prins bicyclization for the synthesis of hexahydrofuro-[3,4-c]furan lignans and octahydropyrano[3,4-c]pyran derivatives

作者：Reddy B V Subba^*; Reddy M Ramana; Sridhar B; Singarapu Kiran Kumar

来源：Organic and Biomolecular Chemistry, 2014, 12(26): 4754-4762.

DOI：10.1039/c4ob00305e

An acetal-initiated Prins bicyclization approach has been developed for the stereoselective synthesis of hexahydrofuro[3,4-c]furan lignans. This also provides a direct way to generate a new series of octahydropyrano[3,4-c]pyran derivatives in a single-step process.

• 出版日期2014