Association of dietary omega-3 fatty acids with prevalence of metabolic syndrome: The National Heart, Lung, and Blood Institute Family Heart Study

作者：Lai Y H Lana; Petrone Andrew B; Pankow James S; Arnett Donna K; North Kari E; Ellison R Curtis; Hunt Steven C; Djousse Luc^*

来源：Clinical Nutrition, 2013, 32(6): 966-969.

DOI：10.1016/j.clnu.2013.05.002

• Omega-3 fatty acids
• Fish
• Dietary alpha-linolenic acid (ALA)
• Metabolic syndrome

Background %26 aims: Metabolic syndrome (MetS), characterized by abdominal obesity, atherogenic dyslipidemia, elevated blood pressure, and insulin resistance is a major public health concern in the United States. Omega-3 fatty acids have been relatively well studied in relation to many individual cardiovascular risk factors; however, their effects on MetS are not well established. %26lt;br%26gt;Methods: We conducted a cross-sectional study consisting of 4941 participants from the National Heart, Lung, and Blood Institute (NHLBI) Family Heart Study to assess the relation of dietary omega-3 fatty acids with the prevalence of MetS. Omega-3 intake was assessed using a food frequency questionnaire and we used generalized estimating equations to estimate adjusted odds ratios for prevalent MetS. %26lt;br%26gt;Results: Our study population had a mean age (SD) of 52.1 (13.9) years and 45.9% were men. The mean (SD) of dietary omega-3 fatty acids was 0.25 g/day (0.27). From the lowest to the highest quintile of dietary omega-3 fatty acids, multivariable adjusted ORs (95% CI) for MetS were 1.00 (ref), 0.90 (0.72 -1.13), 1.03 (0.82-1.28), 0.94 (0.74-1.18), and 0.99 (0.77-1.25), respectively. In a secondary analysis, neither fish consumption nor dietary alpha-linolenic acid was associated with MetS. %26lt;br%26gt;Conclusions: Our findings do not support an association between dietary omega-3 fatty acids and MetS in a large US population.

• 出版日期2013-12