The Elemental Sulfur-Responsive Protein (SipA) from the Hyperthermophilic Archaeon Pyrococcus furiosus Is Regulated by Sulfide in an Iron-Dependent Manner

作者：Clarkson Sonya M; Newcomer Elizabeth C; Young Everett G; Adams Michael W W^*

来源：Journal of Bacteriology, 2010, 192(21): 5841-5843.

DOI：10.1128/JB.00660-10

The gene (sipA) encoding the sulfur-induced protein A (PF2025) is highly upregulated during growth of Pyrococcus furiosus on elemental sulfur (S(0)). Expression of sipA is regulated by sulfide, the product of S(0) reduction, but in an iron-dependent manner. SipA is proposed to play a role in intracellular iron sulfide detoxification.

• 出版日期2010-11