Magnetite-loaded polymeric micelles as ultrasensitive magnetic-resonance probes

作者：Ai H; Flask C; Weinberg B; Shuai X; Pagel MD; Farrell D; Duerk J; Gao JM^*

来源：Advanced Materials, 2005, 17(16): 1949-+.

DOI：10.1002/adma.200401904

Increased contrast in magnetic resonance imaging (MRI) is accomplished using polymeric micelles loaded with superparamagnetic iron oxide (SPIO) nanoparticles encapsulated in biocompatible, biodegradable poly(F-caprolactone) -b-poly(ethylene glycol) (PCL-b-PEG) copolymers (see Figure). The loaded micelles show significantly improved T-2 relaxivities and remarkable MRI detection sensitivity.

• 出版日期2005-8-16