Anti-atherosclerotic mechanisms of statin therapy

作者:Babelova Andrea; Sedding Daniel G; Brandes Ralf P*
来源:Current Opinion in Pharmacology, 2013, 13(2): 260-264.
DOI:10.1016/j.coph.2013.01.004

摘要

HMG-CoA-Reductase inhibitors, also known as statins, are currently the most powerful cholesterol-lowering drugs available on the market. Clinical trials and experimental evidence suggest that statins have anti-atherosclerotic effects. These are in part consequence of lipid lowering but also result from pleiotropic actions of the drugs. In this article, the anti-atherosclerotic actions of statins will be reviewed.

  • 出版日期2013-4