科研之友
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摘要
Neuromyelitis optica (NMO), an inflammatory demyelinating disease, is characterized by the occurrence of optic neuritis and longitudinally extensive transverse myelitis and is easily misdiagnosed as a severe variant of multiple sclerosis (MS). The discovery of AQP4-antibodies in serum of NMO and high-risk (HR) patients enables early diagnosis and specific treatment. In this review, we will give an overview of AQP4-antibodies in serum and cerebrospinal fluid of NMO and HR patients. In addition, the diagnostic and therapeutic relevance of these AQP4-antiboches with regard to the disease course will be discussed.
- 出版日期2010
