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摘要
In this paper, an SVEIS epidemic model for an infectious disease that spreads in the host population through horizontal transmission is investigated. The role that temporary immunity (natural, disease induced, vaccination induced) plays in the spread of disease, is incorporated in the model. The total host population is bounded and the incidence term is of the Holling-type II form. It is shown that the model exhibits two equilibria, namely, the disease-free equilibrium and the endemic equilibrium. The global dynamics are completely determined by the basic reproduction number R-0. If R-0 < 1, the disease-free equilibrium is globally stable which leads to the eradication of disease from population. If R-0 > 1, a unique endemic equilibrium exists and is globally stable in the feasible region under certain conditions. Further, the transcritical bifurcation at R-0 = 1 is explored by projecting the flow onto the extended center manifold. We use the geometric approach for ordinary differential equations which is based on the use of higher-order generalization of Bendixson's criterion. Further, we obtain the threshold vaccination coverage required to eradicate the disease. Finally, taking biologically relevant parametric values, numerical simulations are performed to illustrate and verify the analytical results.
- 出版日期2012-3
