Alternative route for the synthesis of new derivatives of benzimidazo[2 ',1 ':2,3]thiazolo[5,4-d]pyrimidine

作者:Asghari Tayebe; Bakavoli Mehdi*; Eshghi Hossein; Shiri Ali; Ebrahimpour Zahra
来源:Journal of Chemical Research, 2015, 39(9): 539-541.
DOI:10.3184/174751915X14402629597371

摘要

A series of new benzimidazothiazolopyrimidines were synthesised through a route involving successive nucleophilic substitution of 5-bromo-2,4-dichloro-6-methylpyrimidine with 2-mercaptobenzimidazole and secondary amines, respectively and eventually cyclisation in the presence of KOH in DMF. The structures of the newly synthesised compounds were characterised by their spectral data and elemental analysis.

  • 出版日期2015-9