Short Report: Strongyloidiasis Hyperinfection in a Patient with a History of Systemic Lupus Erythematosus

作者:Yung Evan E*; Lee Cassie M K L; Boys Joshua; Grabo Daniel J; Buxbaum James L; Chandrasoma Parakrama T
来源:The American Journal of Tropical Medicine and Hygiene, 2014, 91(4): 806-809.
DOI:10.4269/ajtmh.14-0228

摘要

Strongyloidiasis is a parasitic disease caused by Strongyloides stercoralis, a nematode predominately endemic to tropical and subtropical regions, such as Southeast Asia. Autoinfection enables the organism to infect the host for extended periods. Symptoms, when present, are non-specific and may initially lead to misdiagnosis, particularly if the patient has additional co-morbid conditions. Imrnunosuppressive states place patients at risk for the Strongyloides hyperinfection syndrome (SHS), whereby the organism rapidly proliferates and disseminates within the host. Left untreated, SHS is commonly fatal. Unfortunately, the non-specific presentation of strongyloidiasis and the hyperinfection syndrome may lead to delays in diagnosis and treatment. We describe an unusual case of SHS in a 30-year-old man with a long-standing history of systemic lupus erythematosus who underwent a partial colectomy. The diagnosis was rendered on identification of numerous organisms during histologic examination of the colectomy specimen.

  • 出版日期2014-10