Approaches to neuroscience data integration

作者：Cheung Kei Hoi^*; Lim Ernest; Samwald Matthias; Chen Huajun; Marenco Luis; Holford Matthew E; Morse Thomas M; Mutalik Pradeep; Shepherd Gordon M; Miller Perry L

来源：Briefings in Bioinformatics, 2009, 10(4): 345-353.

DOI：10.1093/bib/bbp029

• data integration
• neuroinformatics
• ontology
• semantic web
• user interface

As the number of neuroscience databases increases, the need for neuroscience data integration grows. This paper reviews and compares several approaches, including the Neuroscience Database Gateway (NDG), Neuroscience Information Framework (NIF) and Entrez Neuron, which enable neuroscience database annotation and integration. These approaches cover a range of activities spanning from registry, discovery and integration of a wide variety of neuroscience data sources. They also provide different user interfaces for browsing, querying and displaying query results. In Entrez Neuron, for example, four different facets or tree views (neuron, neuronal property, gene and drug) are used to hierarchically organize concepts that can be used for querying a collection of ontologies. The facets are also used to define the structure of the query results.

• 出版日期2009-7
• 单位浙江大学