A rhodamine-based "turn-on" fluorescent probe for Fe3+ in aqueous solution and its application in bioimaging

作者：Liu, Yao; Liu, Yaqi; Xu, Zhanhui; Yang, Linchao; Wang, Zhenji; Zhang, Di^*; Ye, Yong^*

来源：Monatshefte fur Chemie, 2016, 147(2): 311-317.

DOI：10.1007/s00706-015-1521-9

• Chemosensor
• Fe3+ ion
• Enhancement
• Naked eye
• Fluorescence imaging

A novel colorimetric and off-on fluorescent chemosensor which contained a strong electron-withdrawing group was synthesized. As expected, the chemosensor exhibited high selectivity and excellent sensitivity in both absorbance and fluorescence detection of Fe3+ (I similar to (CH3OH, H2O) = 3/7, 1 mM Tris-HCl buffer, pH = 7.40). Upon addition of Fe3+, the solution of the chemosensor resulted in a color change from colorless to obvious pink. These significant changes in color could be used for naked-eye detection. Furthermore, fluorescence imaging experiments of Fe3+ ions in living MGC-803 cells demonstrated its value of practical applications in biological systems.

• 出版日期2016-2
• 单位河南省农业科学院; 郑州大学