Utility of blood procalcitonin concentration in the management of cancer patients with infections

作者:Durnas Bonita; Watek Marzena; Wollny Tomasz; Niemirowicz Katarzyna; Marzec Michal; Bucki Robert*; Gozdz Stanislaw
来源:OncoTargets and Therapy, 2016, 9: 469-475.
DOI:10.2147/OTT.S95600

摘要

Diagnosis of infections in cancer patients is usually problematic since differentiating between infection and fever of unknown origin is often a considerable clinical challenge. In general, increase concentration of blood procalcitonin (PCT) is associated with severe bacterial infection. PCT with an optimal cutoff level of 0.5 ng/mL seems to be the most helpful biochemical parameter in detecting severe infections, mainly bloodstream infection, in patients with hematological cancers. In all clinical situations, the elevated level of PCT should be carefully analyzed, always with a thorough physical examination and an appropriate microbiological assessment.

  • 出版日期2016