科研之友
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摘要
The Mitf gene has a key role in melanocytes and melanoma by regulating cell cycle progression, survival and differentiation. Two papers in this issue of Oncogene (Cheli et al., 2011; Strub et al., 2011) reveal that low-Mitf cells can initiate tumors with high efficiency, and that Mitf blocks senescence by regulating genes implicated in S-phase progression and mitosis. Oncogene (2011) 30, 2304-2306; doi: 10.1038/onc.2010.641; published online 31 January 2011
- 出版日期2011-5
