Microbial Hydroxylation of S-(-)-Perillyl Alcohol by Fusarium heterosporium

作者：Kiran Ismail^*

来源：Natural Product Communications, 2011, 6(12): 1805-1806.

• Biotransformation
• Fusarium heterosporium
• S-(-)-perillyl alcohol

S-(-)-Perillyl alcohol (p-mentha-1, 8-diene-7-ol) (1) (500 mg) was converted by Fusarium heterosporium ATCC 15625 over 10 days at 25 degrees C to a new metabolite, 1,2-dihydroxyperillyl alcohol (p-mentha-8-en-1,2,7-triol) (3) in a yield of 13% (70 mg). The structure of 3 was established by IR and NMR spectroscopic, specific rotation, and mass spectral studies.

• 出版日期2011-12