A convenient 1,3-dipolar cycloaddition approach to pyridylpyrroles

作者：Lopchuk Justin M; Gribble Gordon W^*

来源：Tetrahedron Letters, 2011, 52(32): 4106-4108.

DOI：10.1016/j.tetlet.2011.05.111

• Munchnone
• 1,3-Dipolar cycloaddition
• Regioselectiviry
• Nitroalkene
• Henry reaction

A variety of 2-, 3-, and 4-pyridylpyrroles were synthesized in good to excellent yields via the 1,3-dipolar cycloaddition of symmetrical and unsymmetrical munchnones and nitroalkenes. The unsymmetrical munchnones show moderate to excellent regioselectivity.

• 出版日期2011-8-10