A patient with esophageal cancer showing remission of nephrotic syndrome after esophagectomy: report of a case

作者：Ito Hiromitsu^*; Kumagai Youichi; Iida Michio; Yamazaki Shigeru; Odajima Hajime; Kawano Tatsuyuki

来源：Surgery Today, 2013, 43(12): 1452-1456.

DOI：10.1007/s00595-012-0477-1

• Esophageal cancer
• Nephrotic syndrome
• Membranous nephropathy
• Esophagectomy
• Surgical treatment

A 73-year-old male patient was admitted to our hospital due to bilateral leg edema and proteinuria in April 2009. After admission, nephrotic syndrome (membranous nephropathy) was diagnosed. At that point, a cancer screening test was performed; however, no abnormalities were noted. Medical treatment with prednisolone and cyclosporine was started, which resulted in the temporary improvement of markers of laboratory data. The patient was re-examined in November of the same year, and esophageal cancer (squamous cell carcinoma, T2N0M0 Stage IIA according to the UICC TNM classification) was detected in the lower thoracic esophagus. Subtotal esophagectomy was performed via right thoracolaparotomy with two-field lymph node dissection. Although the patient%26apos;s course was complicated by respiratory failure, he was discharged after 38 days. After performing esophagectomy, prompt amelioration of the nephrotic syndrome occurred, allowing the withdrawal of prednisolone and cyclosporine. There has been no recurrence of esophageal cancer or relapse of nephrotic syndrome during a period of 18 months after esophagectomy.

• 出版日期2013-12