New 6/8/6-Taxanes Isolated from the Heartwood of Taxus cuspidata

作者:Zhang, Kai; Li, Yong; Ni, Zhi-Yi; Zhang, Man-Li; Wang, Yu-Fang; Shi, Qing-Wen*; Huo, Chang-Hong; Sauriol, Francoise; Kiyota, Hiromasa; Gu, Yu-Cheng; Dong, Mei
来源:Helvetica Chimica Acta, 2012, 95(9): 1566-1572.
DOI:10.1002/hlca.201200045

摘要

Two new natural taxanes were isolated from the heartwood of Taxus cuspidata. The structures were established as rel-(2a,5a,7 beta,9a,10 beta,12a)-7,9-bis(acetyloxy)-2-(benzoyloxy)-11,12-epoxy-1,5-dihydroxy-10-[(hydroxyacetyl)oxy]tax-4(20)-en-13-one (1), and (2a,5a,10 beta,14 beta)-taxa-4(20),11-diene-2,5,10,14-tetrol 2-acetate (2) on the basis of spectroscopic analysis.