Application of 'next-generation' sequencing technologies to microbial genetics

作者:MacLean Daniel; Jones Jonathan D G; Studholme David J*
来源:Nature Reviews Microbiology, 2009, 7(4): 287-296.
DOI:10.1038/nrmicro2088

摘要

New sequencing methods generate data that can allow the assembly of microbial genome sequences in days. With such revolutionary advances in technology come new challenges in methodologies and informatics. In this article, we review the capabilities of high-throughput sequencing technologies and discuss the many options for getting useful information from the data.

  • 出版日期2009-4