An easy access to fused chromanones via rhodium catalyzed oxidative coupling of salicylaldehydes with heterobicyclic olefins

作者：Vijayan Ajesh; Baiju T V; Jiiy E; Prakash Praveen; Shimi M; Joseph Nayana; Pihko Petri M; Varughese Sunil; Radhakrishnan K V^*

来源：Tetrahedron, 2016, 72(27-28): 4007-4015.

DOI：10.1016/j.tet.2016.05.031

• Chromanone
• Rhodium catalyzed
• Diazabicyclic olefins
• Urea derived bicyclic olefins
• Salicylaldehyde

Herein we describe a detailed study on the rhodium catalyzed oxidative coupling of salicylaldehydes with heterobicyclic olefins such as diazabicyclic olefins and urea-derived bicyclic olefins. The developed method provides an ideal route to fused chromanone systems in a single synthetic step. Moreover, the scope of this methodology was extended to different oxa/aza-bridged bicyclic urea derivatives.

• 出版日期2016-7-7