Stress disrupts context-dependent memory

作者：Schwabe Lars^*; Boehringer Andreas; Wolf Oliver T

来源：Learning & Memory, 2009, 16(2): 110-113.

DOI：10.1101/lm.1257509

Memory is facilitated when the retrieval context resembles the learning context. The brain structures underlying contextual influences on memory are susceptible to stress. Whether stress interferes with context-dependent memory is still unknown. We exposed healthy adults to stress or a control procedure before they learned an object-location task in a room scented with vanilla. Memory was tested 24 h later, either in the same or in a different context (unfamiliar room without the odor). Stress administered prior to encoding abolished the context-dependent memory enhancement found in the control group. Thus, these findings represent the first demonstration of impaired context-dependent memory following stress.

• 出版日期2009-2