A cooperative Pd-Cu system for direct C-H bond arylation

作者：Lesieur Mathieu; Lazreg Faima; Cazin Catherine S J^*

来源：Chemical communications, 2014, 50(64): 8927-8929.

DOI：10.1039/c4cc03201b

A novel and efficient method for C-H arylation using well-defined Pd- and Cu-NHC systems has been developed. This process promotes the challenging construction of C-C bonds from arenes or heteroarenes using aryl bromides and chlorides. Mechanistic studies show that [Cu(OH)(NHC)] plays a key role in the C-H activation and is involved in the transmetallation with the Pd-NHC co-catalyst.

• 出版日期2014-8-18