An Efficient Method for the Nitration of Phenols with NaNO2 in the Presence of 3-Methyl-1-Sulfonic Acid Imidazolium Chloride

作者：Khazaei A^*; Zolfigol M A; Moosavi Zare A R; Zare A

来源：Scientia Iranica, 2010, 17(1): 31-36.

• 3-Methyl-1-sulfonic acid imidazolium chloride {[Msim]Cl}
• Bronsted acidic ionic liquid
• Nitrosation-oxidation
• Nitration
• Nitrophenols
• Sodium nitrite (NaNO2)

Nitrophenols can be obtained in high yields via nitrosation-oxidation of phenols by 3-methyl-1-sulfonic acid imidazolium chloride {[Msim]Cl} as a new Bronsted acidic ionic liquid and NaNO2 at room temperature. In situ generation of HNO2 and a radical-cation mechanism via the nitrous acid catalyzed pathway appear to be applicable to phenol nitration using this reagent system.

• 出版日期2010-6