Embryonic stem cell identity grounded in the embryo

作者:Plusa Berenika*; Hadjantonakis Anna Katerina
来源:Nature Cell Biology, 2014, 16(6): 502-504.
DOI:10.1038/ncb2984

摘要

Pluripotent embryonic stem cells (ESCs) can be derived from blastocyst-stage mouse embryos. However, the exact in vivo counterpart of ESCs has remained elusive. A combination of expression profiling and stem cell derivation identifies epiblast cells from late-stage blastocysts as the source, and functional equivalent, of ESCs.

  • 出版日期2014-6