Stability of tetracycline residues in honey

作者:Cara Monica Cristina; Dumitrel Gabriela Alina*; Glevitzky Mirel; Perju Delia
来源:Journal of the Serbian Chemical Society, 2012, 77(7): 879-886.
DOI:10.2298/JSC111002214C

摘要

The problem of the availability of veterinary medicines to treat honeybees is discussed extensively worldwide. An uncontrolled administration of antibiotics may lead to contamination of beehive products and contribute to the problem of food safety. In this study, the kinetics of tetracycline (TC) degradation in honey was studied for samples provided by four beekeepers located in the west region of Romania. The samples of honey were stored in the dark at room temperature for 30 days and sub-samples were analyzed every 3 days by the Elisa method. The results of the study revealed that the level of tetracycline decreased with time in all the honey samples. The tetracycline degradation followed a first-order kinetic model with reaction rate constants between 1.2x10(3)-2x10(3) days(-1). The half-life time, tau(1/2), of tetracycline in monofloral honeys: acacia and lime was 251 and 232 days, respectively. Tetracycline degradation in the polyfloral honey was accelerated, exhibiting a tau(1/2) of 151 days.

  • 出版日期2012